State MPs will today have a conscience vote on the Research Involving Human Embryos and Prohibition of Human Cloning Amendment Bill 2007, which allows the creation of human embryos by cloning for research.
The bill also allows for the creation of hybrid embryos - the fertilisation of an animal egg by human sperm - but retains prohibitions on placing a human embryo clone in a human or animal's body.
Scientists argue the research has the potential to cure illnesses such as Parkinson's and Alzheimer's.
Premier Anna Bligh, who supports the laws, said she looked forward to hearing a range of views.
"I expect to see a mature debate," Ms Bligh said.
"I think it will be an interesting debate, I think people do have strong views about it, and we will see some of those strong views voiced on the floor of the chamber."
Ms Bligh noted that even without the laws passing, it was possible for corporations to do the research in Queensland, under laws which have already been passed by the federal parliament.
Passing the state laws would allow smaller organisations to undertake the research.
"It is important that people understand a vote against this legislation will not prohibit stem cell research in Queensland," Ms Bligh said.
"But it would certainly deny the opportunity to some research organisations, that just might be the one that has a scientist in it that could make the breakthrough."
Opposition Leader Jeff Seeney, who will also support the laws, said he had asked Coalition MPs to familiarise themselves on all aspects of the debate.
"It's too easy to get carried away with hype and misinformation," Mr Seeney said.
"Everyone needs to read the information and make up their own minds, that's the whole secret to a conscience vote."
High-profile opponents include Attorney-General Kerry Shine and Liberal Leader Bruce Flegg, who say they cannot agree to laws that allow the destruction of human life
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